Ossian Sweet (October 30, 1895 – March 20, 1960) was a American physician. He is most notable for his self-defense in 1925 of his newly purchased home in a white neighborhood against a mob attempting to force him out of the neighborhood in Detroit, Michigan, and the subsequent acquittal by an all-white jury of murder charges against him, his family, and friends who helped defend his home, in what came to be known as the Sweet Trials.