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lymph node labeled - germinal center, marginal sinus, nodule

lymph node labeled - germinal center, marginal sinus, nodule

Germinal center - Germinal center - Wikipedia, the free encyclopedia

Germinal center - Germinal center - Wikipedia, the free encyclopedia

Severe Malaria Infections Impair Germinal Center Responses by Inhibiting T Follicular Helper Cell Differentiation: Cell Reports

Severe Malaria Infections Impair Germinal Center Responses by Inhibiting T Follicular Helper Cell Differentiation: Cell Reports

A very colorful fluorescent micrograph of  a large number of B lymphocytes forming a germinal center. Image by Ann Haberman, Ph.D., associate research scientist. Click for more on Dr. Haberman's research.

A very colorful fluorescent micrograph of a large number of B lymphocytes forming a germinal center. Image by Ann Haberman, Ph.D., associate research scientist. Click for more on Dr. Haberman's research.

Immunohistochemistry: Ogg1 Antibody [NB100-106] - Staining of tonsil, germinal center and mantle zone.

Immunohistochemistry: Ogg1 Antibody [NB100-106] - Staining of tonsil, germinal center and mantle zone.

Histology - Spleen White Pulp with PALS and Central Artery (l.s.) traveling through germinal center...surrounded by red pulp.

Histology - Spleen White Pulp with PALS and Central Artery (l.s.) traveling through germinal center...surrounded by red pulp.

Germinal Center Reactions in T Cell Dependent Antibody Responses Late Events

Germinal Center Reactions in T Cell Dependent Antibody Responses Late Events

Synthetic immune organ produces antibodies- When exposed to a foreign agent, such as an immunogenic protein, B cells in lymphoid organs undergo germinal center reactions. The image on the left is an immunized mouse spleen with activated B cells (brown) that produce antibodies.

Synthetic immune organ produces antibodies- When exposed to a foreign agent, such as an immunogenic protein, B cells in lymphoid organs undergo germinal center reactions. The image on the left is an immunized mouse spleen with activated B cells (brown) that produce antibodies.

- Cortex: lymphoid follicles, secondary lymphoid follicles (mostly B cells), germinal center - Paracortical area (mostly T cells) - Medullary cords (macrophages and plasma cells) - Medullary sinus

- Cortex: lymphoid follicles, secondary lymphoid follicles (mostly B cells), germinal center - Paracortical area (mostly T cells) - Medullary cords (macrophages and plasma cells) - Medullary sinus

Yellow arrows highlight a germinal center with lymphocyte proliferation. € Red arrows point to the lymphocytic infiltrate in which the germi...

Yellow arrows highlight a germinal center with lymphocyte proliferation. € Red arrows point to the lymphocytic infiltrate in which the germi...

A germinal center in a sea of B cell clones. http://science.sciencemag.org/content/early/2016/02/17/science.aad3439.full.pdf+html

A germinal center in a sea of B cell clones. http://science.sciencemag.org/content/early/2016/02/17/science.aad3439.full.pdf+html

SPLEEN (follicle) Stained with haematoxylin and eosin lymphoid follicle is circled with dotted line 1 - germinal center of the follicle 2 - mantie zone of the follicle 3 - marginal zone of the follicle 4 - periarterial area of the follicle 5 - central arteriole 6 - red pulp 7 - trabeculae

SPLEEN (follicle) Stained with haematoxylin and eosin lymphoid follicle is circled with dotted line 1 - germinal center of the follicle 2 - mantie zone of the follicle 3 - marginal zone of the follicle 4 - periarterial area of the follicle 5 - central arteriole 6 - red pulp 7 - trabeculae

SHANE CROTTY  B cells (green) interacting with CD4+T cells (red) in the germinal center.

SHANE CROTTY B cells (green) interacting with CD4+T cells (red) in the germinal center.

Germinal center of immunized mouse.

Germinal center of immunized mouse.

SPLEEN (follicle)       Stained with haematoxylin and eosin       lymphoid follicle is circled with        dotted line  1 - marginal zone of the follicle  2 - mantie zone of the follicle  3 - germinal center of the follicle  4 - periarterial area of the follicle  5 - central arteriole  6 - red pulp  7 - trabeculae

SPLEEN (follicle) Stained with haematoxylin and eosin lymphoid follicle is circled with dotted line 1 - marginal zone of the follicle 2 - mantie zone of the follicle 3 - germinal center of the follicle 4 - periarterial area of the follicle 5 - central arteriole 6 - red pulp 7 - trabeculae