Loss of the ability to add a special sugar called 'O-GlcNAc' to intracellular proteins via an enzyme known as OGT induces many hallmarks of neurodegeneration in mice. Furthermore tissues from human Alzheimer's patients show significant loss of OGT.
WHAT IS KARMA? The term “karma” is often used with great casualness, with little understanding of its profundity. People dismissively say “it’s my karma,” suggesting that their destiny or fate is merely the luck or bad fortune of the draw.