Relationship between life and death. inside, outside: No information about this but it is two different photographs put together to create a half skull, half face image. That heavily relates to the theme of inside, outside and in between.
The iconic image of MC Escher's Reptiles lithograph from 1943 has become part of a global cultural legacy. This is particularly true in the technology world where it not only explores tessellations in Mathematics, but also dabbles in a playful absurdity.